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Preclinical research

 

In vivo screening

 

In order to conduct a proof-of-concept study to evaluate the potential of an anticancer therapy, it is critical that the compound be well administered to animals.
The required process is based on the following:

  • Preclinical formulation
  • Dose determination
  • Route & schedule of administration
  • Antitumor activity

In vivo pharmacology

 

Following the screening process, we subsequently evaluate the activity of the compound in more clinically-relevant tumor models.

  • Orthotopic & metastatic models
  • Transgenic & chemo-induced models
  • Nude rat xenograft models
  • Primary tumor models
 
 
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