Bioanalysis - Biotech QC
Access over 20 years’ expertise in the development and validation of assay methods
Our experience and highly qualified teams can support you with selecting the best appropriate assay method in accordance with your needs, the Good Professional practices and international standards.
The quantification of the biomarkers identified can be performed in liquid or tissular environments.
Oncodesign harnesses classic technologies such as immuno-analysis, chemical analysis and molecular biology, mass flow cytometry (CyTOF) and cellular sorting in BSL3 conditions. We have several BSL3 installations in which we process infectious specimens. We also offer combined technologies such as HPLC-MS2.
Analysis of your New Chemical and Biological Entities
Development and validation of analytical methods for drugs:
- Improvement and validation of analytical methods for drugs
- Technology for transferring analytical methods for drugs
- Systematic analysis of drugs
Analysis of membrane proteins
The level of protein expression and an understanding of the proteins’ functional roles, such as in the drug’s absorption, distribution, metabolism, elimination, toxicity and efficacy (ADME-T/efficacy) are important for drug discovery and development.
Oncodesign’s exclusive MS2Plex® offering quantifies membrane proteins in a GLP environment such as CYPs, UGTs, ABC and SLC carriers involved in ADME-T studies for drug candidates.
Immuno-monitoring of patients
Oncodesign has a set of skills and equipment dedicated to monitoring innate and adapted immune responses in cell cultures, or after administration of a drug candidate in animals (non-human primates - NHPs, mice or other animal species), healthy volunteers and patients.
This immuno-monitoring aims to establish the efficacy and safety of vaccines, adjuvants and immune therapies.
Immuno-analysis
Oncodesign possesses an integrated offering from development through to routine assay of your compounds in liquid and tissular environments. This offering is performed in a certified Good Laboratory Practice environment:
• Custom development of dosage methods
• Update and validation of biomarker dosages
• Bioanalysis supporting translational research and preclinical and clinical studies
• Supply of ready-to-use dosage kits customized for implementation either in your facilities or in medical analysis labs.
Microbiological monitoring
Oncodesign manages the samples collected from volunteers and from patients enrolled in clinical trials. We can work as a central laboratory and provide you with a range of management solutions for your samples in our biobank.
We can also handle the microbiological monitoring of your infectious samples (class 2 and class 3 human pathogens, including transmissible respiratory agents such as influenza virus) in our Level 2 and 3 Biosecurity laboratories.
In parallel with its innovative bioanalysis tools, Oncodesign can provide you with the benefit of its expertise in the analysis of biological compounds. We have technology platforms enabling us to cover all the stages in the protein characterization process. We provide solutions geared to performing the quality control tests in compliance with the current guidelines to guarantee the identity, purity, load, biological activity and viral/prion security of the final product.